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DGCR6L 抗体 (Biotin)

DGCR6L 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1405813
发货至: 中国
  • 抗原 See all DGCR6L 抗体
    DGCR6L (DiGeorge Syndrome Critical Region Gene 6-Like (DGCR6L))
    适用
    • 46
    • 17
    • 16
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 45
    • 1
    克隆类型
    • 46
    多克隆
    标记
    • 13
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    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This DGCR6L antibody is conjugated to Biotin
    应用范围
    • 36
    • 18
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DGCR6L
    亚型
    IgG
    Top Product
    Discover our top product DGCR6L Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    DGCR6L (DiGeorge Syndrome Critical Region Gene 6-Like (DGCR6L))
    别名
    DGCR6L (DGCR6L 产品)
    别名
    DGCR6L antibody, DiGeorge syndrome critical region gene 6-like antibody, DiGeorge syndrome critical region gene 6 like antibody, DGCR6L antibody
    背景

    Synonyms: DGC6L_HUMAN, DGCR6L, DiGeorge syndrome critical region 6-like protein, Protein DGCR6L.

    Background: Neural crest cell migration to the third and fourth pharyngeal pouches is a critical step in the structural formation of organs that are affected in DiGeorge syndrome. DGCR6 (DiGeorge syndrome critical region 6) is a nuclear protein that plays a role in neural crest cell migration and is located at the DiGeorge syndrome critical region (DGCR) on chromosome 22. Expressed ubiquitously with highest levels in heart, liver and skeletal muscle, DGCR6 shares high homology with the Drosophila gonadal (gdl) protein and with human Laminin-1, both of which are involved in early tissue development. The gene encoding DGCR6, along with other DGCR genes, is deleted in DiGeorge syndrome, a developmental disorder characterized by improper facial, cardiac and palate formation. Upregulation of DGCR6 is implicated in lung and colon adenocarcinomas, as well as in Burkitt?s lymphoma and lymphocytes transformed by EBV. Due to a duplication of the ancestral DGCR6 locus, there are two functional, highly homologous copies of the DGCR6 gene (designated DGCR6 and DGCR6L) on chromosome 22.

    基因ID
    85359
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