SRI 抗体 (AbBy Fluor® 647)
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- 抗原 See all SRI 抗体
- SRI (Sorcin (SRI))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SRI antibody is conjugated to AbBy Fluor® 647
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SR1/Sorcin
- 亚型
- IgG
- Top Product
- Discover our top product SRI Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SRI (Sorcin (SRI))
- 别名
- Sorcin (SRI 产品)
- 别名
- zgc:64070 antibody, sri antibody, SRI antibody, CP-22 antibody, CP22 antibody, SCN antibody, V19 antibody, 2210417O06Rik antibody, 2900070H08Rik antibody, Sor antibody, sorcin antibody, Sorcin antibody, sorcin L homeolog antibody, sorcin S homeolog antibody, SRI antibody, sri antibody, EDI_060410 antibody, EDI_160670 antibody, EDI_002860 antibody, EDI_076560 antibody, CpipJ_CPIJ004933 antibody, CpipJ_CPIJ008581 antibody, Tsp_05707 antibody, sri.L antibody, sri.S antibody, Sri antibody
- 背景
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Synonyms: 22 kDa protein, Calcium binding protein amplied in mutlidrug resistant cells, CP 22, CP-22, CP22, SCN, Sorcin class 4 gene, Sorcin, SORCN_HUMAN, SRI, V19.
Background: Sorcin is a highly conserved protein, with 95 % homology between hamster and human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin EF hand? motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain and sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to and modulates ryanodine receptors and is widely distributed including heart and brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.
- 基因ID
- 6717
- 途径
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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