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INTS3 抗体 (AA 960-998) (Biotin)

INTS3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1404541
发货至: 中国
  • 抗原 See all INTS3 抗体
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    抗原表位
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 960-998
    适用
    • 27
    • 19
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 27
    克隆类型
    • 27
    多克隆
    标记
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INTS3 antibody is conjugated to Biotin
    应用范围
    • 23
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human INTS3
    亚型
    IgG
    Top Product
    Discover our top product INTS3 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    别名
    INTS3 (INTS3 产品)
    别名
    INTS3 antibody, Ints3 antibody, NV18802 antibody, ACYPI009450 antibody, DL3335W antibody, FCAALL.260 antibody, embryo defective 2739 antibody, C1orf193 antibody, C1orf60 antibody, INT3 antibody, SOSS-A antibody, C77668 antibody, RGD1304593 antibody, si:dkey-27c15.2 antibody, integrator complex subunit 3 antibody, integrator complex subunit 3 L homeolog antibody, embryo defective 2739 antibody, INTS3 antibody, ints3.L antibody, CpipJ_CPIJ008133 antibody, ints3 antibody, Ints3 antibody, LOC100168776 antibody, emb2739 antibody
    背景

    Synonyms: INT3, SOSSA, SOSS-A, C1orf60, C1orf193, Integrator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INTS3

    Background: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.

    基因ID
    65123
    UniProt
    Q68E01
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