PTPLA 抗体 (AbBy Fluor® 350)
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- 抗原 See all PTPLA 抗体
- PTPLA (Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A (PTPLA))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTPLA antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Brd4/CAP
- 亚型
- IgG
- Top Product
- Discover our top product PTPLA Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PTPLA (Protein Tyrosine Phosphatase-Like (Proline Instead of Catalytic Arginine), Member A (PTPLA))
- 别名
- CAP (PTPLA 产品)
- 别名
- HACD1 antibody, CAP antibody, hacd1 antibody, ptpla antibody, 3-hydroxyacyl-CoA dehydratase 1 antibody, 3-hydroxyacyl-CoA dehydratase 1 L homeolog antibody, Hacd1 antibody, HACD1 antibody, hacd1.L antibody
- 背景
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Synonyms: Brd4, BRD4_HUMAN, bromodomain containing protein 4, Bromodomain-containing protein 4, CAP, chromosome associated protein, HUNK1, Protein HUNK1.
Background: Brd4 belongs to the BET family, a group of structurally related proteins containing two bromodomains. Through these two domains, Brd4 associates with mitotic chromosomes and its expression correlates with cell growth. Expression of Brd4 inhibits cell cycle progression from G(1) to S, due to binding to the largest subunit of replication factor C (RFC) to prevent DNA elongation. Altered Brd4 function correlates with poorly differentiated carcinoma, with aggresive phenotype and a highly lethal outcome.
- 基因ID
- 23476
- UniProt
- O60885
- 途径
- Regulation of long-term Neuronal Synaptic Plasticity
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