ANKRD20A3 抗体 (Biotin)
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- 抗原 See all ANKRD20A3 products
- ANKRD20A3 (Ankyrin Repeat Domain 20 Family, Member A3 (ANKRD20A3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANKRD20A3 antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ANKRD20A3
- 亚型
- IgG
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- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ANKRD20A3 (Ankyrin Repeat Domain 20 Family, Member A3 (ANKRD20A3))
- 别名
- ANKRD20A3 (ANKRD20A3 产品)
- 别名
- ankyrin repeat domain 20 family member A3 antibody, ANKRD20A3 antibody
- 背景
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Synonyms: Ankyrin repeat domain 20 family member A3, Ankyrin repeat domain 20A related, Ankyrin repeat domain containing protein 20A3, MGC176486, MGC198508, A20A3_HUMAN.
Background: Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD20A (ankyrin repeat domain-containing protein 20A) is an 823 amino acid protein that contains five ANK repeats. The gene encoding ANKRD20A maps to chromosome 9, which consists of about 145 million bases and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and familial dysautonomia are associated with chromosome 9. Also, chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.
- 基因ID
- 441425
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