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BIN2 抗体 (AbBy Fluor® 555)

BIN2 适用: 人, 大鼠, 小鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN1404311
发货至: 中国
  • 抗原 See all BIN2 抗体
    BIN2 (Bridging Integrator 2 (BIN2))
    适用
    • 47
    • 15
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 46
    • 1
    克隆类型
    • 46
    • 1
    多克隆
    标记
    • 14
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This BIN2 antibody is conjugated to AbBy Fluor® 555
    应用范围
    • 36
    • 18
    • 17
    • 13
    • 12
    • 5
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human BIN2/BRAP1
    亚型
    IgG
    Top Product
    Discover our top product BIN2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    BIN2 (Bridging Integrator 2 (BIN2))
    别名
    BIN2 (BIN2 产品)
    别名
    BRAP-1 antibody, BIN2 antibody, bin2l antibody, wu:fi05e01 antibody, zgc:55758 antibody, bridging integrator 2 antibody, bridging integrator 2b antibody, BIN2 antibody, Bin2 antibody, bin2b antibody
    背景

    Synonyms: BIN2, BIN2_HUMAN, BRAP 1, Breast cancer associated protein BRAP1, Breast cancer-associated protein 1, Bridging integrator 2.

    Background: BAR proteins are characterized by a common N-terminal BAR (bin, amphiphysin and Rvs161/167) domain and are recognized as adaptor proteins that are involved in many cellular processes. BIN1 and BIN2 are BAR proteins that share 61 % sequence similarity. BIN1 (Bridging integrator 1) is a ubiquitously expressed regulatory protein for synaptic vesicle endocytosis. BIN1 also interacts with the transcription factors c-Myc and MyoD, potentially functioning as a tumor suppressor. BIN2, also known as Breast cancer-associated protein 1, is a 565 amino acid protein that interacts with BIN1. In contrast to BIN1, BIN2 lacks tumor suppressor features as well as a c-Myc interacting region. BIN2 shows preferred expression in tissues of hematopoietic origin, with high levels found in spleen, thymus, colon, placenta, lymphoid and granulocytic cells. There are two isoforms of BIN2 that are produced as a result of alternative splicing events.

    基因ID
    51411
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