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MYLIP 抗体 (AA 65-103) (Biotin)

MYLIP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1404013
发货至: 中国
  • 抗原 See all MYLIP 抗体
    MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
    抗原表位
    • 14
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-103
    适用
    • 40
    • 36
    • 21
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 40
    • 2
    克隆类型
    • 40
    • 2
    多克隆
    标记
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYLIP antibody is conjugated to Biotin
    应用范围
    • 33
    • 16
    • 13
    • 13
    • 7
    • 5
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MYLIP
    亚型
    IgG
    Top Product
    Discover our top product MYLIP Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))
    别名
    MYLIP (MYLIP 产品)
    别名
    IDOL antibody, MIR antibody, 9430057C20Rik antibody, Mir antibody, mylip antibody, wu:fj36b03 antibody, zgc:55987 antibody, MYLIP antibody, mir antibody, zgc:153767 antibody, myosin regulatory light chain interacting protein antibody, myosin regulatory light chain interacting protein a antibody, myosin regulatory light chain interacting protein L homeolog antibody, myosin regulatory light chain interacting protein b antibody, MYLIP antibody, Mylip antibody, mylipa antibody, mylip.L antibody, mylip antibody, mylipb antibody
    背景

    Synonyms: MIR, IDOL, E3 ubiquitin-protein ligase MYLIP, Inducible degrader of the LDL-receptor, Myosin regulatory light chain interacting protein, MYLIP, BZF1, BM-023, PP5242

    Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

    基因ID
    29116
    UniProt
    Q8WY64
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