C18orf1 抗体 (AA 1-50) (Biotin)
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- 抗原 See all C18orf1 抗体
- C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
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抗原表位
- AA 1-50
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C18orf1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human C18orf1
- 亚型
- IgG
- Top Product
- Discover our top product C18orf1 Primary Antibody
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anti-Chromosome 18 Open Reading Frame 1 (C18orf1) (AA 1-306) antibody
C18orf1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Chromosome 18 Open Reading Frame 1 (C18orf1) (AA 176-225) antibodyC18orf1 适用: 人, 小鼠, 大鼠, Cow, 马, Bat, 小鸡, 猴, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- C18orf1 (Chromosome 18 Open Reading Frame 1 (C18orf1))
- 别名
- C18orf1 (C18orf1 产品)
- 别名
- C18orf1 antibody, 8230401C20Rik antibody, A430083H02 antibody, A430108L08Rik antibody, D18Ertd653e antibody, D330030L18Rik antibody, low density lipoprotein receptor class A domain containing 4 antibody, LDLRAD4 antibody, Ldlrad4 antibody
- 背景
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Synonyms: C18orf1, Low-density lipoprotein receptor class A domain-containing protein 4, LDLRAD4
Background: Functions as a negative regulator of TGF-beta signaling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
- 基因ID
- 753
- UniProt
- O15165
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