KCTD11 抗体 (AbBy Fluor® 488)
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- 抗原 See all KCTD11 抗体
- KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KCTD11 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KCTD11
- 亚型
- IgG
- Top Product
- Discover our top product KCTD11 Primary Antibody
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anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (AA 21-53) antibody
KCTD11 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB54391 unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (AA 41-90) antibodyKCTD11 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 豚鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (AA 61-110) antibodyKCTD11 适用: 人, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (Internal Region) antibodyVerified KCTD11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (N-Term) antibodyKCTD11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 11 (KCTD11) (N-Term) antibodyKCTD11 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- KCTD11 (Potassium Channel Tetramerisation Domain Containing 11 (KCTD11))
- 别名
- KCTD11 (KCTD11 产品)
- 别名
- KCTD11 antibody, AF465352 antibody, Ren antibody, C17orf36 antibody, KCASH1 antibody, REN antibody, REN/KCTD11 antibody, potassium channel tetramerization domain containing 11 antibody, potassium channel tetramerisation domain containing 11 antibody, KCTD11 antibody, Kctd11 antibody
- 背景
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Synonyms: C17orf36, MGC 129844, Potassium channel tetramerisation domain containing 11, REN, Retinoic acid EGF NGF induced gene protein, C 17 orf 36, KCD11_HUMAN.
Background: The KCTD11 gene encodes a protein that has been identified as a suppressor of Hedgehog signaling. Its inactivation might lead to a deregulation of the tumor promoting Hedgehog pathway in medulloblastoma. Plays a role as a marker and a regulator of neuronal differentiation, Up-regulated by a variety of neurogenic signals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growth arrest and the expression of cyclin-dependent kinase inhibitor CDKN1B. Plays a role as a tumor repressor and inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Functions as antagonist of the Hedgehog pathway on cell proliferation and differentiation by affecting the nuclear transfer of transcrition factor GLI1, thus maintaining cerebellar granule cells in undifferentiated state.
- 基因ID
- 147040
- 途径
- Hedgehog Signaling
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