PARP16 抗体 (AA 120-170) (Biotin)
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- 抗原 See all PARP16 抗体
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
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抗原表位
- AA 120-170
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARP16 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PARP16
- 亚型
- IgG
- Top Product
- Discover our top product PARP16 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- PARP16 (Poly (ADP-Ribose) Polymerase Family, Member 16 (PARP16))
- 别名
- PARP16 (PARP16 产品)
- 别名
- PARP16 antibody, zgc:77744 antibody, ARTD15 antibody, C15orf30 antibody, pART15 antibody, BC055447 antibody, C79952 antibody, PARP-16 antibody, LRRGT00109 antibody, RGD1306243 antibody, poly(ADP-ribose) polymerase family member 16 antibody, poly(ADP-ribose) polymerase family member 16 L homeolog antibody, poly (ADP-ribose) polymerase family, member 16 antibody, PARP16 antibody, parp16.L antibody, parp16 antibody, Parp16 antibody
- 背景
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Synonyms: C15orf30, Chromosome 15 open reading frame 30, EC 2.4.2.30, FLJ25281, PAR16_HUMAN, PARP 16, PARP-16, Parp16, Poly ADP ribose polymerase family member 16, Poly [ADP ribose] polymerase 16, Poly [ADP-ribose] polymerase 16.
Background: Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death. The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, thereby preventing cell death. PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, a process that, when repeated multiple times, leads to the formation of poly(ADPribose) chains on the protein. The presence of these chains alters the function of the target protein and promotes cell survival. PARP proteins are implicated in a variety of diseases, including cancer, neurodegenerative and inflammatory disorders. PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane. Expressed as three isoforms produced by alternative splicing, PARP-16 contains one PARP catalytic domain.
- 基因ID
- 54956
- UniProt
- Q8N5Y8
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