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PDE4DIP 抗体 (AbBy Fluor® 350)

PDE4DIP 适用: 人, 小鼠, 大鼠 IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1402941
发货至: 中国
  • 抗原 See all PDE4DIP 抗体
    PDE4DIP (phosphodiesterase 4D Interacting Protein (PDE4DIP))
    适用
    人, 小鼠, 大鼠
    宿主
    • 21
    • 3
    克隆类型
    • 23
    • 1
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDE4DIP antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 12
    • 8
    • 3
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human CMYA2/PDE4DIP
    亚型
    IgG
    Top Product
    Discover our top product PDE4DIP Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PDE4DIP (phosphodiesterase 4D Interacting Protein (PDE4DIP))
    别名
    CMYA2 (PDE4DIP 产品)
    背景

    Synonyms: Cardiomyopathy associated protein 2, Cardiomyopathy-associated protein 2, CMYA2, MMGL, MYOME_HUMAN, Myomegalin, Pde4dip, Phosphodiesterase 4D interacting protein, Phosphodiesterase 4D-interacting protein.

    Background: May function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.Myomegalin, is a 2,346 amino acid protein that contains one NBPF domain and localizes to the nucleus, cytoplasm, centrosome and Golgi apparatus. Expressed at high levels in fetal and adult heart and at lower levels in brain and placenta, myomegalin is thought to function as an anchoring protein that sequesters members of the cAMP-dependent pathway to the Golgi and to centrosomes, thereby mediating cAMP pathway dynamics. Translocations in the gene that encodes myomegalin are associated with myeloproliferative disorders (MBDs), a group of diseases caused by an overproduction of blood cells. Myomegalin exists as twelve isoforms due to alternative splicing events.

    基因ID
    9659
    途径
    SARS-CoV-2 Protein Interactome
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