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PYGB 抗体 (Biotin)

GPBB 适用: 人, 小鼠, 大鼠 IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1402801
发货至: 中国
  • 抗原 See all PYGB (GPBB) 抗体
    PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
    适用
    • 62
    • 46
    • 29
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    人, 小鼠, 大鼠
    宿主
    • 71
    • 5
    克隆类型
    • 71
    • 5
    多克隆
    标记
    • 29
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    This PYGB antibody is conjugated to Biotin
    应用范围
    • 45
    • 33
    • 14
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GPBB/PYGB
    亚型
    IgG
    Top Product
    Discover our top product GPBB Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
    别名
    GPBB (GPBB 产品)
    别名
    GPBB antibody, GLYPHOA antibody, glycogen phosphorylase B antibody, phosphorylase, glycogen; brain antibody, brain glycogen phosphorylase antibody, phosphorylase, glycogen; brain S homeolog antibody, PYGB antibody, pygb antibody, Pygb antibody, pygb.S antibody
    背景

    Synonyms: Brain glycogen phosphorylase, Glycogen phosphorylase B, Glycogen phosphorylase brain form, Glycogen Phosphorylase Isoenzyme BB, Glycogen phosphorylase, brain form, MGC9213, Phosphorylase glycogen brain, PYGB, PYGB_HUMAN.

    Background: Glycolysis is an evolutionarily conserved series of ten chemical reactions that utilizes eleven enzymes to concomitantly generate pyruvate and ATP from glucose. fructose kinase-2/fructose 2,6-bisphosphatase (PFK-2) stimulates the synthesis and degradation of fructose 2,6-bisphosphate. Glycogen phosphorylase (also known as GP) is an allosteric enzyme important in carbohydrate metabolism. Its activity is regulated through either noncovalent binding of metabolites or by covalent modification. Glycogen phosphorylase catalyzes the phosphorylation of glycogen to Glc-1-P. There are three genes which encode the brain, liver and muscle forms of glycogen phosphorylase, PYGB, PYGL and PYGM. Because of its fundamental role in the metabolism of glycogen, glycogen phosphorylase has been a target for the design of inhibitory compounds, which could be valuable in the therapeutic treatment of type 2 diabetes mellitus.

    基因ID
    5834
    途径
    Cellular Glucan Metabolic Process
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