RNF31 抗体 (Biotin)
-
- 抗原 See all RNF31 抗体
- RNF31 (Ring Finger Protein 31 (RNF31))
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RNF31 antibody is conjugated to Biotin
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF31
- 亚型
- IgG
- Top Product
- Discover our top product RNF31 Primary Antibody
-
anti-Ring Finger Protein 31 (RNF31) (Middle Region) antibody
RNF31 适用: 人, 小鼠, 大鼠, 兔, 犬, Cow, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 955-983), (C-Term) antibodyRNF31 适用: 人 WB 宿主: 兔 Polyclonal RB39346 unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 421-700) antibodyRNF31 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (C-Term) antibodyVerified RNF31 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) antibodyRNF31 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) antibodyRNF31 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 68-405) antibodyRNF31 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (C-Term) antibodyRNF31 适用: 人, 兔, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein 31 (RNF31) (AA 500-700) antibodyRNF31 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
-
- 抗原
- RNF31 (Ring Finger Protein 31 (RNF31))
- 别名
- RNF31 (RNF31 产品)
- 别名
- RNF31 antibody, HOIP antibody, ZIBRA antibody, AL033293 antibody, BC031509 antibody, Flj10111 antibody, Paul antibody, mFLJ00217 antibody, ring finger protein 31 antibody, RNF31 antibody, rnf31 antibody, Rnf31 antibody
- 背景
-
Synonyms: HOIP, ZIBRA, E3 ubiquitin-protein ligase RNF31, HOIL-1-interacting protein, RING finger protein 31, Zinc in-between-RING-finger ubiquitin-associated domain protein, RNF31
Background: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
- 基因ID
- 55072
- UniProt
- Q96EP0
-
