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SLFN14 抗体 (Biotin)

SLFN14 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1401361
发货至: 中国
  • 抗原 See all SLFN14 products
    SLFN14 (Schlafen Family Member 14 (SLFN14))
    适用
    人, 小鼠, 大鼠
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLFN14 antibody is conjugated to Biotin
    应用范围
    • 16
    • 13
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SLFN14
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    SLFN14 (Schlafen Family Member 14 (SLFN14))
    别名
    SLFN14 (SLFN14 产品)
    别名
    LRRGT00163 antibody, Gm20 antibody, Slfn14-ps antibody, schlafen family member 14 antibody, protein SLFN14 antibody, schlafen family member 11 antibody, schlafen 14 antibody, Slfn14 antibody, LOC491140 antibody, SLFN14 antibody, SLFN11 antibody, LOC100021434 antibody, LOC100358198 antibody
    背景

    Synonyms: Schlafen family member 14, SLFN14, SLN14_HUMAN.

    Background: Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.

    基因ID
    342618
    UniProt
    P0C7P3
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