RLIM 抗体 (AA 550-600) (Biotin)
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- 抗原 See all RLIM 抗体
- RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))
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抗原表位
- AA 550-600
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RLIM antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF12
- 亚型
- IgG
- Top Product
- Discover our top product RLIM Primary Antibody
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anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-83) antibody
RLIM 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1G10 unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 199-227) antibodyRLIM 适用: 人 WB 宿主: 兔 Polyclonal RB42228 unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-624) antibodyRLIM 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 532-581) antibodyRLIM 适用: 人, 犬, 马, Cow, 兔, Pig, Bat, 小鸡, Hamster, 猴, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (C-Term) antibodyRLIM 适用: 人, 小鼠, 大鼠, 犬, 马, Cow, 豚鼠, 兔, Pig, Saccharomyces cerevisiae, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 550-600) antibodyRLIM 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-83) antibodyRLIM 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 1-624) antibodyRLIM 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (N-Term) antibodyRLIM 适用: 人, 犬, 马, 豚鼠, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ring Finger Protein, LIM Domain Interacting (RLIM) (AA 535-624) antibodyRLIM 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))
- 别名
- RNF12 (RLIM 产品)
- 别名
- NY-REN-43 antibody, RNF12 antibody, AL022832 antibody, AW743871 antibody, Ha1r antibody, Rnf12 antibody, R-LIM antibody, ring finger protein, LIM domain interacting antibody, XRnf12C protein antibody, RLIM antibody, Rlim antibody, xrnf12c antibody, rlim antibody
- 背景
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Synonyms: RNF12, NY-REN-43, E3 ubiquitin-protein ligase RLIM, LIM domain-interacting RING finger protein, RING finger LIM domain-binding protein, R-LIM, RING finger protein 12, Renal carcinoma antigen NY-REN-43, RLIM
Background: E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.
- 基因ID
- 51132
- UniProt
- Q9NVW2
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