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ZNRF2 抗体 (AbBy Fluor® 555)

ZNRF2 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN1401065
发货至: 中国
  • 抗原 See all ZNRF2 抗体
    ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))
    适用
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    人, 小鼠, 大鼠
    宿主
    • 39
    • 1
    克隆类型
    • 33
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    多克隆
    标记
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    This ZNRF2 antibody is conjugated to AbBy Fluor® 555
    应用范围
    • 22
    • 12
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human ZNRF2
    亚型
    IgG
    Top Product
    Discover our top product ZNRF2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ZNRF2 (Zinc and Ring Finger 2 (ZNRF2))
    别名
    ZNRF2 (ZNRF2 产品)
    别名
    RNF202 antibody, 1190002C14Rik antibody, AU044205 antibody, D6Ertd365e antibody, zgc:152865 antibody, znrf2 antibody, Znrf1 antibody, zgc:171663 antibody, zinc and ring finger 2 antibody, zinc and ring finger 2b antibody, zinc and ring finger 2a antibody, ZNRF2 antibody, Znrf2 antibody, znrf2b antibody, znrf2a antibody
    背景

    Synonyms: E3 ubiquitin-protein ligase ZNRF2, Protein Ells2, RING finger protein 202, Zinc/RING finger protein 2, Znrf2, ZNRF2_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). ZNRF2 (zinc and ring finger 2), also known as RNF202, is a 242 amino acid peripheral membrane protein that contains one RING-type zinc finger and localizes to the lysosome, as well as the endosome and the cell junction. Expressed at high levels in brain tissue, ZNRF2 is thought to function as an E3 ubiquitin-protein ligase that may be involved in the establishment and maintenance of neuronal transmission and plasticity. Upon DNA damage, ZNRF2 is subject to phosphorylation, probably by ATR or ATM.

    基因ID
    223082
    途径
    Synaptic Membrane
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