BAGE2 抗体 (Biotin)
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- 抗原 See all BAGE2 products
- BAGE2 (B Melanoma Antigen Family, Member 2 (BAGE2))
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAGE2 antibody is conjugated to Biotin
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BAGE2
- 亚型
- IgG
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anti-B Melanoma Antigen Family, Member 2 (BAGE2) antibody
BAGE2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B Melanoma Antigen Family, Member 2 (BAGE2) antibodyBAGE2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- BAGE2 (B Melanoma Antigen Family, Member 2 (BAGE2))
- 别名
- BAGE2 (BAGE2 产品)
- 别名
- CT2.2 antibody, BAGE family member 2 antibody, BAGE2 antibody
- 背景
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Synonyms: B melanoma antigen 2, B melanoma antigen family, member 2, Cancer/testis antigen 2.2, CT2.2, BAGE2_HUMAN.
Background: Members of the BAGE gene family encode antigens that are recognized by cytotoxic T lymphocytes and are also known as CT (cancer/testis) antigens. Generated by juxtacentromeric shuffling of the MLL3 gene, the ancestral BAGE gene was expanded by acrocentric exchanges and/or juxtacentromeric movements.Generally, BAGE proteins are silent in all normal tissues with the exception of testis. BAGE2 and BAGE 3 (B melanoma antigen 2 and 3, respectively), also known as Cancer/testis antigen 2.2 and 2.3 (respectively), are 109 amino acid secreted proteins that are expressed in 22 % of melanomas, lung and bladder carcinomas, and are also expressed in normal testis tissue. Like the genes encoding MAGE proteins, BAGE genes are most likely silenced by DNA methylation and/or chromatin compaction in normal tissues other than testis.
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