HDGFRP2 抗体 (Biotin)
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- 抗原 See all HDGFRP2 抗体
- HDGFRP2 (Hepatoma-Derived Growth Factor-Related Protein 2 (HDGFRP2))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HDGFRP2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human HRP2
- 亚型
- IgG
- Top Product
- Discover our top product HDGFRP2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- HDGFRP2 (Hepatoma-Derived Growth Factor-Related Protein 2 (HDGFRP2))
- 别名
- HRP2 (HDGFRP2 产品)
- 别名
- HDGF2 antibody, Hdgf2 antibody, hdgf2 antibody, hrp2 antibody, HRP-2 antibody, HDGF like 2 antibody, HDGF like 2 L homeolog antibody, HDGFL2 antibody, Hdgfl2 antibody, hdgfl2.L antibody
- 背景
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Synonyms: HDGF-2, Hdgfrp2, HDGR2_HUMAN, Hepatoma-derived growth factor 2, Hepatoma-derived growth factor, Hepatoma-derived growth factor-related protein 2, heptoma derived growth factor related protein 2, HRP-2.
Background: Hepatoma Derived Growth Factor (HDGF) is the original member of a family of polypeptides designated HDGF-related proteins (HRPs). HDGF was initially characterized as a secreted mitogen from the Huh-7 human hepatoma cell line. This nuclear targeted vascular smooth muscle cell mitogen (VSM) is a heparin-binding protein that is highly expressed in tumor cells where it stimulates proliferation. HDGF is also reported to be involved in organ development and lung remodeling after injury by promoting proliferation of lung epithelial cells. During development, HDGF expression is high in the nucleus and cytoplasm of smooth muscle and endothelial cells. The HRP (HDGF related proteins) family contains four proteins, HRP-1, HRP-2, HRP-3 and HRP-4. HRP-1 and HRP-4 are only expressed in testis while HRP-2 is widely expressed in different tissues. HRP-3 can solely be found in the nervous system. Specifically it is strongly expressed in bulbus, olfactorius, piriform cotrex and amygdala complex while HRP-2 in brain is located in the the thalamus, prefrontal and parietal cortex, neurohypophysis, and the cerebellum. In the central nervous system, HRP proteins are play a role in neuron proliferation and cell survival.
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