TRPM5 抗体 (AbBy Fluor® 555)
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- 抗原 See all TRPM5 抗体
- TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TRPM5 antibody is conjugated to AbBy Fluor® 555
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TRPM5
- 亚型
- IgG
- Top Product
- Discover our top product TRPM5 Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))
- 别名
- TRPM5 (TRPM5 产品)
- 别名
- LTRPC5 antibody, MTR1 antibody, 9430099A16Rik antibody, LTrpC-5 antibody, Ltrpc5 antibody, Mtr1 antibody, transient receptor potential cation channel subfamily M member 5 antibody, transient receptor potential cation channel, subfamily M, member 5 antibody, TRPM5 antibody, Trpm5 antibody, trpm5 antibody
- 背景
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Synonyms: MLSN1 and TRP related gene 1, MLSN1 and TRP related gene 1 protein, MLSN1 and TRP-related, MLSN1- and TRP-related gene 1 protein, MTR1, Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5 , Transient receptor potential cation channel subfamily M member 5, Transient receptor potential cation channel, subfamily M, member 5, Trpm5, TRPM5 transient receptor potential cation channel, subfamily M, member 5, TRPM5_HUMAN, 9430099A16Rik, Long transient receptor potential channel 5, LTrpC-5, LTrpC5.
Background: Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.
- 基因ID
- 29850
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