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PDZD4 抗体 (AbBy Fluor® 350)

PDZD4 适用: 人, 小鼠, 大鼠 WB, IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1400481
发货至: 中国
  • 抗原 See all PDZD4 products
    PDZD4 (PDZ Domain Containing 4 (PDZD4))
    适用
    • 32
    • 24
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 32
    克隆类型
    • 32
    多克隆
    标记
    • 9
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PDZD4 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 32
    • 12
    • 12
    • 3
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PDZK4
    亚型
    IgG
  • 应用备注
    IF(IHC-P) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PDZD4 (PDZ Domain Containing 4 (PDZD4))
    别名
    PDZK4 (PDZD4 产品)
    别名
    LU1 antibody, PDZK4 antibody, PDZRN4L antibody, B230341P03 antibody, D130075J17Rik antibody, Kiaa1444-hp antibody, Pdzk4 antibody, Pdzrnk4l antibody, Xlu antibody, PDZ domain containing 4 antibody, PDZD4 antibody, Pdzd4 antibody
    背景

    Synonyms: FERM and PDZ domain containing protein 2, PDZ domain containing protein 4, PDZ domain containing protein 5C, PDZ domain containing 4 PDZD5C, PDZK4, PDZK5C,FRPD2_HUMAN.

    Background: PDZK4, also known as PDZRN4L (PDZ domain-containing RING finger protein 4-like protein) or LU1, is a 769 amino acid coiled-coil protein that contains one PDZ (DHR) domain. Encoded by a gene that maps to human chromosome Xq28, PDZK4 is conserved in dog, cow, mouse, rat and zebrafish. PDZK4 localizes to cytoplasm and is expressed specifically in adult and fetal brain. PDZK4 functions as an oncogene and is up-regulated in synovial carcinomas. Treatment of synovial sarcoma cells with small interfering RNA (siRNA) inhibits PDZK4 expression, resulting in tumor-cell growth suppression, suggesting that inappropriate expression of PDZK4 may play a role synovial sarcoma cell proliferation.The exact function of FRMPD2 is unknown. The protein contains a FERM domain: such structures are often involved in signal transduction pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.

    基因ID
    143162
    UniProt
    Q68DX3
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