IQCG 抗体 (AbBy Fluor® 350)
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- 抗原 See all IQCG 抗体
- IQCG (IQ Motif Containing G (IQCG))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IQCG antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human IQCG
- 亚型
- IgG
- Top Product
- Discover our top product IQCG Primary Antibody
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anti-IQ Motif Containing G (IQCG) (AA 1-134) antibody
IQCG 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-IQ Motif Containing G (IQCG) antibodyIQCG 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- IQCG (IQ Motif Containing G (IQCG))
- 别名
- IQCG (IQCG 产品)
- 别名
- 2400003L07Rik antibody, RGD1311606 antibody, IQ motif containing G antibody, IQCG antibody, iqcg antibody, Iqcg antibody
- 背景
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Synonyms: IQ domain containing protein G, IQ mot containing G, DKFZp434B227, FLJ11667, FLJ23571, FLJ37775, IQCG_HUMAN.
Background: IQCG is a 443 amino acid protein containing one IQ domain. Widely distributed in nature, the IQ domain forms an amphiphilic seven-turn -helix capable of binding calmodulin in a Ca2+-independent manner. The level of intracellular calcium is tightly regulated in all eukaryotic cells. A modest increase in this level can result in a myriad of physiological responses, most of which are mediated by calmodulin (CaM), the universal calcium sensor. In acute T-lymphoid/myeloid leukemia, IQCG forms a complex with Nup98, an O-linked glycoprotein and a component of the nuclear pore complex. NUP98-IQCG complex bind co-activators and/or co-repressors, which suggest a role in transcriptional regulation.Nup98-IQCG complex inhibits 32Dcl3 cell apoptosis induced by Arabinofuranosylcytosine (Ara-C) and partially blocks granulocyte differentiation induced by G-CSF. IQCG exists as two isoforms due to alternatively splicing events.
- 基因ID
- 84223
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