ANKRD6 抗体 (AbBy Fluor® 488)
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- 抗原 See all ANKRD6 抗体
- ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ANKRD6 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ANKRD6/Diversin
- 亚型
- IgG
- Top Product
- Discover our top product ANKRD6 Primary Antibody
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anti-Ankyrin Repeat Domain 6 (ANKRD6) (AA 314-343) antibody
ANKRD6 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB32838 unconjugated
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ANKRD6 (Ankyrin Repeat Domain 6 (ANKRD6))
- 别名
- ANKRD6 (ANKRD6 产品)
- 别名
- ANKRD6 antibody, ankrd6 antibody, diversin antibody, si:dkey-181i3none antibody, ankyrin repeat domain 6 antibody, ankyrin repeat domain 6b antibody, ANKRD6 antibody, ankrd6b antibody, Ankrd6 antibody
- 背景
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Synonyms: ANKRD 6, ankyrin repeat domain 6, ANKR6_HUMAN, Ankyrin repeat domain-containing protein 6, Diversin.
Background: Diversin, also known as ANKRD6 (ankyrin repeat domain 6), is a 727 amino acid protein that contains eight ankyrin repeats and belongs to the ankyrin repeat domain protein family. Members of the ankyrin repeat domain family facilitate protein-protein interactions and function as adaptors of signaling pathways. Expressed in a developmentally-regulated manner and at highest levels in the brain, Diversin is believed to play a role in brain development. Via its ankyrin repeats, Diversin can directly interact with Dvl (dishevelled), an interaction that is essential for the activation of noncanonical Wnt signaling. In addition, Diversin contains a C-terminal domain that binds Axin/Conductin and a casein kinase-binding domain in its central region that specifically binds casein kinase I?. Through the action of these additional domains, Diversin may also facilitate canonical Wnt signaling. Due to alternative splicing events, three Diversin isoforms exist.
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