MEPE 抗体 (AA 201-300) (Biotin)
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- 抗原 See all MEPE 抗体
- MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
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抗原表位
- AA 201-300
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEPE antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MEPE
- 亚型
- IgG
- Top Product
- Discover our top product MEPE Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- MEPE (Matrix Extracellular phosphoglycoprotein (MEPE))
- 别名
- MEPE (MEPE 产品)
- 别名
- OF45 antibody, OC-116 antibody, Of45 antibody, matrix extracellular phosphoglycoprotein antibody, matrix extracellular phosphoglycoprotein with ASARM motif (bone) antibody, MEPE antibody, Mepe antibody, LOC789774 antibody
- 背景
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Synonyms: Matrix extracellular phosphoglycoprotein, MEPE, MEPE_HUMAN, OF45, Osteoblast/osteocyte factor 45.
Background: MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers.
- 基因ID
- 56955
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