ELL 抗体 (AA 531-620) (Biotin)
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- 抗原 See all ELL 抗体
- ELL (Elongation Factor RNA Polymerase II (ELL))
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抗原表位
- AA 531-620
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ELL antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ELL
- 亚型
- IgG
- Top Product
- Discover our top product ELL Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- ELL (Elongation Factor RNA Polymerase II (ELL))
- 别名
- ELL (ELL 产品)
- 别名
- wu:fc60b11 antibody, zgc:63836 antibody, C19orf17 antibody, ELL1 antibody, MEN antibody, PPP1R68 antibody, Ell1 antibody, Men antibody, elongation factor for RNA polymerase II antibody, elongation factor RNA polymerase II antibody, ELL antibody, ell antibody, Ell antibody
- 背景
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Synonyms: ELL_HUMAN, Eleven nineteen lysine rich leukemia gene, Eleven-nineteen lysine-rich leukemia protein, ELL1, elongation factor RNA polymerase II, Men, RNA polymerase II elongation factor, RNA polymerase II elongation factor ELL.
Background: Eukaryotic RNA polymerase II mediates the synthesis of mature and functional messenger RNA. This is a multistep process, called the transcription cycle, that includes five stages: preinitiation, promoter, clearance, elongation and termination. Elongation is thought to be a critical stage for the regulation of gene expression. ELL (11-19 lysine-rich leukemia protein), also designated MEN, functions as an RNA polymerase II elongation factor that increases the rate of transcription by suppressing transient pausing by RNA polymerase II. It is also thought to regulate cellular proliferation. ELL is abundantly expressed in peripheral blood leukocytes, skeletal muscle, placenta and testis, with lower expression in spleen, thymus, heart, brain, lung, kidney, liver and ovary. The gene encoding human ELL, which maps to chromosome 19p13.1, is one of several genes that undergo translocation with the MLL gene on chromosome 11q23 in acute myeloid leukemia. MLL (myeloid/lymphoid leukemia, also designated ALL-1 and HRX) regulates embryonal and hematopoietic development.
- 基因ID
- 8178
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