FBXO11 抗体 (AA 65-160) (Biotin)
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- 抗原 See all FBXO11 抗体
- FBXO11 (F-Box Protein 11 (FBXO11))
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抗原表位
- AA 65-160
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FBXO11 antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FBXO11
- 亚型
- IgG
- Top Product
- Discover our top product FBXO11 Primary Antibody
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anti-F-Box Protein 11 (FBXO11) (AA 744-843) antibody
FBXO11 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 65-160) antibodyFBXO11 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) antibodyFBXO11 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 1-843) antibodyFBXO11 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 744-844) antibodyFBXO11 适用: 人 WB, ELISA, IF, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-F-Box Protein 11 (FBXO11) (Middle Region) antibodyFBXO11 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 犬, 豚鼠, 兔 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (Internal Region) antibodyFBXO11 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 181-453) antibodyFBXO11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (AA 754-765) antibodyVerified FBXO11 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-F-Box Protein 11 (FBXO11) (C-Term) antibodyFBXO11 适用: 人, 小鼠, 大鼠, 马, 斑马鱼, 犬, 豚鼠, 兔, 非洲爪蟾, 小鸡, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- FBXO11 (F-Box Protein 11 (FBXO11))
- 别名
- FBXO11 (FBXO11 产品)
- 背景
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Synonyms: UBR6, VIT1, FBX11, PRMT9, UG063H01, F-box only protein 11, Protein arginine N-methyltransferase 9, Vitiligo-associated protein 1, VIT-1, FBXO11
Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DTL/CDT2, BCL6 and PRDM1/BLIMP1. The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells. The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53.
- 基因ID
- 80204
- UniProt
- Q86XK2
- 途径
- Sensory Perception of Sound
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