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GCOM1 抗体 (AA 51-150) (Biotin)

GCOM1 适用: 小鼠 WB, ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1398883
发货至: 中国
  • 抗原 See all GCOM1 抗体
    GCOM1 (GRINL1A Complex Locus (GCOM1))
    抗原表位
    • 14
    • 2
    • 1
    • 1
    • 1
    AA 51-150
    适用
    • 17
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 21
    克隆类型
    • 21
    多克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GCOM1 antibody is conjugated to Biotin
    应用范围
    • 21
    • 13
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GCOM1
    亚型
    IgG
    Top Product
    Discover our top product GCOM1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    GCOM1 (GRINL1A Complex Locus (GCOM1))
    别名
    GCOM1 (GCOM1 产品)
    别名
    GRINL1A antibody, Gcom2 antibody, MYZAP antibody, MYZAP-POLR2M antibody, gcom antibody, GRINL1A complex locus 1 antibody, GCOM1 antibody
    背景

    Synonyms: Gcom2, Glutamate receptor ionotropic N methyl D aspartate like 1A combined, GRINL1A, GRINL1A combined protein, GRINL1A combined protein Gcom12, GRINL1A upstream protein, Gup1, Gup2, NMDAR1 subunit interacting protein.

    Background: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. Gcom1 (GRINL1A complex locus protein 1), also known as GUP (GRINL1A upstream protein) and Gcom (GRINL1A combined protein), is a 466 amino acid protein that is a component of the GRINL1A complex transcription unit, which is thought to be involved in the modulation of glutamatergic neurotransmission through interaction with the NR1 subunit of the NMDA receptor. Gcom1 is expressed in small intestine, lung, liver, heart, skeletal muscle, testis and prostate and also colocalizes with NR1 in cortical and hippocampal neurons. There are eleven isoforms of Gcom1 that are produced as a result of alternative splicing events.

    基因ID
    145781
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