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Keratan Sulfate 抗体 (AA 251-350) (AbBy Fluor® 488)

KS 适用: 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1396929
发货至: 中国
  • 抗原 See all Keratan Sulfate (KS) 抗体
    Keratan Sulfate (KS)
    抗原表位
    AA 251-350
    适用
    • 16
    • 16
    • 3
    • 1
    • 1
    • 1
    大鼠, 小鼠
    宿主
    • 15
    • 3
    克隆类型
    • 15
    • 3
    多克隆
    标记
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratan Sulfate antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 18
    • 14
    • 12
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Keratan Sulfate
    亚型
    IgG
    Top Product
    Discover our top product KS Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Keratan Sulfate (KS)
    别名
    Keratan Sulfate (KS 产品)
    背景

    Synonyms: Carbohydrate chondroitin 6 keratan sulfotransferase 1, Carbohydrate chondroitin 6 keratan sulfotransferase, Carbohydrate keratan sulfate Gal 6 sulfotransferase, Carbohydrate keratan sulfate Gal 6 sulfotransferase 1, Carbohydrate sulfotransferase 1, CHST1, EC 2.8.2.21, Galactose N acetylglucosamine N acetylglucosamine 6 O sulfotransferase 1, GST 1 antibody Keratan sulfate Gal 6 sulfotransferase, KS6ST, KSGAL6ST, KSST.

    Background: Catalyzes the transfer of sulfate to position 6 of galactose residues of keratan. It has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal galactose residues are sulfated. It also may function in the sulfation of sialyl N-acetyllactosamine oligosaccharide chains attached to glycoproteins. It participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Aggrecan is the major proteoglycan of human articular cartilage. The core protein is substituted by a number of keratan sulfate and chondroitin sulfate glycosaminoglycan chains. Whereas chondroitin sulfate is widely distributed throughout the body, keratan sulfate is primarily expressed in cartilage (joints, trachea, intervertebral discs) and cornea.

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