SLC51B 抗体 (AbBy Fluor® 350)
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- 抗原 See all SLC51B (OSTBETA) 抗体
- SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC51B antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB)
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human OST-beta
- 亚型
- IgG
- Top Product
- Discover our top product OSTBETA Primary Antibody
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- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
- 别名
- Ost-beta (OSTBETA 产品)
- 别名
- Ostb antibody, Ostbeta antibody, RGD1565748 antibody, OSTB antibody, OSTBETA antibody, solute carrier family 51, beta subunit antibody, solute carrier family 51 beta subunit antibody, Slc51b antibody, SLC51B antibody
- 背景
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Synonyms: organic solute transporter beta Ostbeta, Organic solute transporter subunit beta, Ostbeta, Ost beta, OST-beta, OSTB, OSTB_HUMAN.
Background: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.
- 基因ID
- 123264
- 途径
- Regulation of Carbohydrate Metabolic Process
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