GABRQ 抗体 (AA 211-320) (AbBy Fluor® 555)
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- 抗原 See all GABRQ 抗体
- GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))
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抗原表位
- AA 211-320
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABRQ antibody is conjugated to AbBy Fluor® 555
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human GABRQ/GABA A Receptor ta
- 亚型
- IgG
- Top Product
- Discover our top product GABRQ Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GABRQ (gamma-aminobutyric Acid (GABA) Receptor, theta (GABRQ))
- 别名
- GABRQ/GABA A Receptor theta (GABRQ 产品)
- 别名
- THETA antibody, gamma-aminobutyric acid type A receptor theta subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit theta antibody, GABRQ antibody, Gabrq antibody
- 背景
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Synonyms: gamma aminobutyric acid GABA receptor, theta, Gamma aminobutyric acid receptor theta subunit precursor, gamma aminobutyric acid receptor, theta, THETA, GBRT_HUMAN.
Background: Gamma-aminobutyric acid type A (GABAA) receptors mediate inhibitory neurotransmission in the mammalian central nervous system. The receptor exists as a pentameric ion channel composed by heteromeric combinations of alpha, beta, gamma, delta, epsilon, theta, or pi subunits. Only specific subunit combinations produce viable receptors, while others never translocate to the cell surface from the ER where they are synthesized, and subsequently degraded. The theta subunit forms a receptor in combination with alpha3 subunits in monoaminergic cell groups. These receptors, found especially in the septum, preoptic areas, hypothalamic nuclei, amygdala and thalamus, likely have unique pharmacological properties linked to their expression in this particular cell type and not cholinergic cell groups, and may play a role in opiate withdrawl symptoms.
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