GDE1 抗体 (AA 231-331) (Biotin)
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- 抗原 See all GDE1 抗体
- GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
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抗原表位
- AA 231-331
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GDE1 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MIR16/GDE1
- 亚型
- IgG
- Top Product
- Discover our top product GDE1 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GDE1 (Glycerophosphodiester Phosphodiesterase 1 (GDE1))
- 别名
- MIR16/GDE1 (GDE1 产品)
- 别名
- zgc:56068 antibody, zgc:77135 antibody, 363E6.2 antibody, MIR16 antibody, 1200003M13Rik antibody, Mir16 antibody, RGS16 antibody, glycerophosphodiester phosphodiesterase 1 antibody, glycerophosphodiester phosphodiesterase 1 L homeolog antibody, gde1 antibody, gde1.L antibody, GDE1 antibody, Gde1 antibody
- 背景
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Synonyms: EC 3.1.4.44, GDE1, Glycerophosphodiester phosphodiesterase 1, Membrane interacting protein of RGS16, RGS16 interacting membrane protein, GDE1_HUMAN.
Background: GDE1 is a 331 amino acid multi-pass membrane protein that localizes to both the membrane and the cytoplasm and contains one GDPD domain. Expressed in a wide variety of tissues, GDE1 uses magnesium as a cofactor to catalyze the conversion of 1-(sn-glycero-3-phospho)-1D-myo-inositol to myo-inositol and sn-glycerol 3-phosphate, an event that is modulated by G protein signaling pathways and provides a link between phosphoinositide metabolism and G protein signal transduction. The gene encoding GDE1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
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