Paralemmin 抗体 (AA 130-230) (Biotin)
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- 抗原 See all Paralemmin (PALM) 抗体
- Paralemmin (PALM)
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抗原表位
- AA 130-230
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Paralemmin antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Paralemmin 1
- 亚型
- IgG
- Top Product
- Discover our top product PALM Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- Paralemmin (PALM)
- 别名
- Paralemmin 1 (PALM 产品)
- 别名
- PALM antibody, palm antibody, zgc:110136 antibody, paralemmin antibody, paralemmin 1a antibody, paralemmin S homeolog antibody, PALM antibody, palm1a antibody, palm antibody, palm.S antibody, Palm antibody
- 背景
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Synonyms: KIAA0270, PALM, PALM_HUMAN, Paralemmin, Paralemmin1,Paralemmin-1.
Background: Paralemmin, also called Paralemmin-1 or PALM, is a widely expressed peripheral membrane protein that is involved in cell structure and shape. A hydrophobic protein, Paralemmin is anchored to the cytoplasmic side of the cell membrane via di-palmitoylation and prenylation of its C-terminal cysteine cluster. Functioning at the synapse to regulate neuronal plasticity and plasma membrane dynamics, Paralemmin can bind to the dopamine receptor D3, thereby reducing D3 expression and subsequent adenylate cyclase activity. Overexpression of Paralemmin induces fibroblasts to extend long filopodia and to assume extreme cell shapes, suggesting involvement in the formation and stabilization of the plasma membrane. Two isoforms of Paralemmin exists due to alternative splicing events.
- 途径
- cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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