NTSR2 抗体 (AA 151-250) (Biotin)
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- 抗原 See all NTSR2 抗体
- NTSR2 (Neurotensin Receptor 2 (NTSR2))
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抗原表位
- AA 151-250
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NTSR2 antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Neurotensin Receptor 2
- 亚型
- IgG
- Top Product
- Discover our top product NTSR2 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- NTSR2 (Neurotensin Receptor 2 (NTSR2))
- 别名
- Neurotensin Receptor 2 (NTSR2 产品)
- 别名
- NTSR2 antibody, NTR2 antibody, NT2R antibody, NTRL antibody, neurotensin receptor 2 antibody, NTSR2 antibody, Ntsr2 antibody
- 背景
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Synonyms: Levocabastine sensitive neurotensin receptor, Levocabastine-sensitive neurotensin receptor, Neurotensin receptor type 2, NT R 2, NT-R-2, NTR2, NTR2 receptor, NTR2_HUMAN, Ntsr2.
Background: Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). NT has a wide distribution in regions of the brain and in peripheral tissues where NT receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a 5-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1beta and TNF?in an ERK1/2 and Akt kinase-dependent manner.
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