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NUMBL 抗体 (AA 75-120) (AbBy Fluor® 488)

NUMBL 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1394416
发货至: 中国
  • 抗原 See all NUMBL 抗体
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    抗原表位
    • 14
    • 9
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    AA 75-120
    适用
    • 46
    • 9
    • 9
    • 1
    宿主
    • 44
    • 1
    • 1
    克隆类型
    • 45
    • 1
    多克隆
    标记
    • 12
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUMBL antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 31
    • 22
    • 16
    • 12
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NUMBL
    亚型
    IgG
    Top Product
    Discover our top product NUMBL Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NUMBL (Numb Homolog (Drosophila)-Like (NUMBL))
    别名
    NUMBL (NUMBL 产品)
    别名
    nbl antibody, numb antibody, cag3a antibody, ctg3a antibody, numbr antibody, numb-r antibody, tnrc23 antibody, numblike antibody, CAG3A antibody, CTG3a antibody, NBL antibody, NUMB-R antibody, NUMBLIKE antibody, NUMBR antibody, TNRC23 antibody, NUMB like, endocytic adaptor protein antibody, numb homolog-like L homeolog antibody, NUMB-like, endocytic adaptor protein antibody, numb-like antibody, NUMBL antibody, numbl.L antibody, Numbl antibody
    背景

    Synonyms: CAG 3A, CAG3A, CTG 3a, CTG3a, NBL, NUMB Drosophilia Homolog Like, Numb homolog Drosophila like, Numb homolog like, Numb like protein, NUMB R, Numb-like protein, Numb-R, Numb-related protein, NUMBL, NUMBL_HUMAN, NUMBR, TNRC 23, TNRC23.

    Background: In Drosophila, neuronal cell fate decisions are directed by NUMB, a signaling adapter protein with two protein-protein interaction domains, namely a phosphotyrosine-binding domain and a proline-rich SH3-binding region (PRR). The mammalian NUMB homolog plays a role in the determination of cell fate during development and binds with a variety of proteins, including Eps15, LNX1 and Notch 1. NumbL (NUMB-like protein), also known as Numb-R, NBL, CAG3A, CTG3a, NUMBLIKE or TNRC23, is a 609 amino acid cytoplasmic protein that, like NUMB, is thought to play a role in cell fate. Expressed at high levels in developing brain tissue, NumbL contains one PID (phosphotyrosine interaction domain) and plays an important role in neuronal differentiation, possibly associating with Eps15 and Notch 1. In mice, deletion of the NumbL gene is associated with early embryonic death, suggesting an essential role for NumbL in early development.

    途径
    Cell-Cell Junction Organization
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