SPOCK1 抗体 (AbBy Fluor® 647)
-
- 抗原 See all SPOCK1 抗体
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SPOCK1 antibody is conjugated to AbBy Fluor® 647
-
应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SPOCK1/Testican 1
- 亚型
- IgG
- Top Product
- Discover our top product SPOCK1 Primary Antibody
-
-
- 应用备注
- IF(IHC-P) 1:50-200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SPOCK1 (Sparc/osteonectin, Cwcv and Kazal-Like Domains Proteoglycan (Testican) 1 (SPOCK1))
- 别名
- Spock1/Testican 1 (SPOCK1 产品)
- 别名
- SPOCK antibody, TESTICAN antibody, TIC1 antibody, Spock antibody, Ticn1 antibody, testican antibody, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1 antibody, sparc/osteonectin, cwcv and kazal like domains proteoglycan 1 antibody, sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1 antibody, SPOCK1 antibody, Spock1 antibody
- 背景
-
Synonyms: Sparc/osteonectin, cwcv and kazal like domains proteoglycan 1, SPOCK, Testican 1, Testican1, Testican-1, TIC1, TICN1, TICN1_HUMAN.
Background: The Testican family, also designated the BM-40/SPARC/osteonectin family, is composed of highly conserved, extracellular, calcium-binding, sulfate proteoglycans. Expression of Testicans is detected in a variety of tissues, but is most abundant in brain. Family members include Testican-1, Testican-2, Testican-3 and an amino-terminal splice variant of Testican-3, designated N-Tes. Most Testicans inhibit MT-MMPs, thereby inhibiting the activity of pro-MMP-2. Testican-1 is specifically expressed in the thalamus of the brain, and is upregulated in activated astroglial cells of the cerebrum where it mediates neuronal attachment and matrix metalloproteinase activation. After a neural injury, such as a cerebral stroke, Testican-1 expression is upregulated in astrocyte cells in order to inhibit the ability of the protein Neuro-2a to form neurite extensions. Testican-1 is also a component of joint and of the growth plate cartilage that may participate in the regulation of matrix turnover.
-