Chromosome 12 Open Reading Frame 52 (C12orf52) (AA 51-150) 抗体 (Biotin)
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- 抗原 See all Chromosome 12 Open Reading Frame 52 (C12orf52) 抗体
- Chromosome 12 Open Reading Frame 52 (C12orf52)
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抗原表位
- AA 51-150
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- Human,Cow,Sheep
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RITA/C12orf52
- 亚型
- IgG
- Top Product
- Discover our top product C12orf52 Primary Antibody
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- Chromosome 12 Open Reading Frame 52 (C12orf52)
- 别名
- RITA/C12orf52 (C12orf52 产品)
- 别名
- RITA antibody, C12orf52 antibody, AI853657 antibody, C86297 antibody, Rita antibody, RBPJ interacting and tubulin associated 1 antibody, RBPJ interacting and tubulin associated 1 L homeolog antibody, RITA1 antibody, rita1.L antibody, Rita1 antibody
- 背景
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Synonyms: C12orf52, Chromosome 12 open reading frame 52, RBPJ-interacting and tubulin-associated protein, RITA, RITA_HUMAN.
Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf52 gene product has been provisionally designated C12orf52 pending further characterization.
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