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NME4 抗体 (AA 21-120) (Biotin)

NME4 适用: 小鼠 WB, ELISA, IHC (p), IHC (fro) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1394005
发货至: 中国
  • 抗原 See all NME4 抗体
    NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))
    抗原表位
    • 14
    • 7
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120
    适用
    • 35
    • 19
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 49
    • 3
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 23
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NME4 antibody is conjugated to Biotin
    应用范围
    • 43
    • 18
    • 17
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Cow,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NME4/nm23-H4
    亚型
    IgG
    Top Product
    Discover our top product NME4 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    NME4 (NME/NM23 Nucleoside Diphosphate Kinase 4 (NME4))
    别名
    NME4/nm23-H4 (NME4 产品)
    别名
    NDPK-D antibody, NM23H4 antibody, nm23-H4 antibody, 2610027N22Rik antibody, 2810024O08Rik antibody, 5730493H09Rik antibody, NM23-M4 antibody, Nm23M4 antibody, NME/NM23 nucleoside diphosphate kinase 4 antibody, NME4 antibody, Nme4 antibody
    背景

    Synonyms: mitochondrial, NDK, NDKM_HUMAN, NDP kinase, NDP kinase, mitochondrial, NDPKD, nm23 H4, nm23-H4, NM23D, Nm23M4, NME4, Non metastatic cells 4 protein expressed in, Nucleoside diphosphate kinase D, Nucleoside diphosphate kinase, mitochondrial.

    Background: The nm23 gene (Metastasis inhibition factor nm23), a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. Based on sequence analysis, nm23, also designated nucleoside diphosphate kinase A (NDK A) or Tumor metastatic process-associated protein, appears to be highly related to nucleotide diphosphate kinases (NDP). NDP kinases A and B are identical to two isotypes of human nm23 homologs, nm23-H1 and nm23-H2, respectively. nm23-H2 is also identical in sequence to PuF, a transcription factor that binds to nuclease-hypersensitive elements at positions 142 to 115 of the human c-Myc promoter. nm23-H3 and nm23-H4 are important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis. nm23-H4 localizes to the mitochondrial intermembrane space and is widely expressed, with higher levels detected in prostate, heart, liver, small intestine, and skeletal muscle tissues. Low amounts of nm23-H4 are observed in the brain and in blood leukocytes.

    途径
    Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process
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