MTPN 抗体 (AA 41-118) (AbBy Fluor® 488)
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- 抗原 See all MTPN 抗体
- MTPN (Myotrophin (MTPN))
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抗原表位
- AA 41-118
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MTPN antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Myotrophin/GCDP
- 亚型
- IgG
- Top Product
- Discover our top product MTPN Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- MTPN (Myotrophin (MTPN))
- 别名
- Myotrophin/GCDP (MTPN 产品)
- 别名
- MGC76285 antibody, GCDP antibody, V-1 antibody, Gcdp antibody, wu:fa10f07 antibody, zgc:64078 antibody, 5033418D15Rik antibody, V1 antibody, myotrophin antibody, myotrophin S homeolog antibody, mtpn antibody, MTPN antibody, Mtpn antibody, mtpn.S antibody
- 背景
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Synonyms: FLJ31098, FLJ99857, GCDP, Granule cell dferentiation protein, MTPN, MTPN_HUMAN, Myotrophin, Protein V 1, Protein V-1, V 1, MTPN_HUMAN.
Background: Myotrophin (V-1 protein) is a ubiquitously expressed cytoplasmic protein that can translocate to the nucleus during sustained NFkB activation. The gene encoding for this protein localizes to chromosome 7q33. Myotrophin may be involved in cerebellar morphogenesis and contains an acetylated N-terminus and 2.5 internal 33 amino acid ankyrin repeats. It is important in the differentiation of cerebellar neurons, particularly of granule cells. The 117 amino acid protein has been associated with, and able to induce, cardiac hypertrophy. Myotrophin increases protooncogene, ANF and Beta-Myosin heavy chain transcript levels. Myotrophin is upregulated when myocytes undergo cyclic stretch or are treated with tumor necrosis factor Alpha (TNF Alpha) or interleukin-1Beta. Highest levels of Myotrophin are detected in brain and lowest levels in skeletal muscle.
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