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KIAA0319 抗体 (AA 682-760) (AbBy Fluor® 488)

KIAA0319 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 488
产品编号 ABIN1393762
发货至: 中国
  • 抗原 See all KIAA0319 抗体
    KIAA0319
    抗原表位
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    AA 682-760
    适用
    • 29
    • 8
    • 6
    • 5
    • 4
    • 2
    宿主
    • 28
    • 2
    克隆类型
    • 30
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KIAA0319 antibody is conjugated to AbBy Fluor® 488
    应用范围
    • 24
    • 12
    • 12
    • 10
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DYX2/KIAA0319
    亚型
    IgG
    Top Product
    Discover our top product KIAA0319 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    KIAA0319
    别名
    DYX2/KIAA0319 (KIAA0319 产品)
    别名
    DYLX2 antibody, DYX2 antibody, 4930451E12Rik antibody, Kiaa0319 antibody, KIAA0319 antibody, RIKEN cDNA D130043K22 gene antibody, KIAA0319 ortholog antibody, similar to mKIAA0319 protein antibody, KIAA0319 antibody, D130043K22Rik antibody, RGD1307443 antibody
    背景

    Synonyms: DLX 2, DLX2, DYLX 2, DYLX2, Dyslexia susceptibility 2, Dyslexia-associated protein KIAA0319 DYX 2, DYX2, K0319_HUMAN, Kiaa0319, MGC176717.

    Background: DYX2 is a 1072 amino acid single-pass transmembrane protein that contains one MANSC domain and two PKD (Polycystic Kidney Disease) domains, which are usually found in the extracellular regions of proteins and are involved in protein-protein interactions. In DYX2, it is likely that its PKD domains mediate the interaction between neurons and glial fibers during neuronal migration. When overexpressed, this plasma membrane protein colocalizes with EEA1 (early endosome antigen 1) in large intracellular vesicles, suggesting that it is endocytosed and recycled. DYX2 is highly expressed in brain cortex, cerebellum, amygdala, putamen and hippocampus. Defects in the gene encoding DYX2 may be the cause of dyslexia type 2, a relatively common disorder that is characterized by reading performance impairment in the absence of sensory or neurologic disability. There are three isoforms of DYX2 that are produced as a result of alternative splicing events

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