Ensa 抗体 (AA 51-121) (AbBy Fluor® 350)
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- 抗原 See all Ensa (ENSA) 抗体
- Ensa (ENSA) (Endosulfine alpha (ENSA))
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抗原表位
- AA 51-121
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Ensa antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ENSA/ARPP-19
- 亚型
- IgG
- Top Product
- Discover our top product ENSA Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Ensa (ENSA) (Endosulfine alpha (ENSA))
- 别名
- ENSA/ARPP-19 (ENSA 产品)
- 别名
- ARPP-19e antibody, 1700020C18Rik antibody, 2610007F17Rik antibody, AI451924 antibody, ensa antibody, si:dkeyp-24a7.3 antibody, ensaa antibody, endosulfine alpha antibody, endosulfine alpha a antibody, endosulfine alpha S homeolog antibody, ENSA antibody, Ensa antibody, ensa antibody, ensaa antibody, ensa.S antibody
- 背景
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Synonyms: Alpha endosulfine, ARPP 19e, Endosulfine alpha, ENSA_HUMAN.
Background: Sulfonylureas are a class of drugs commonly used in the management of noninsulin-dependent diabetes mellitus. ENSA/ARPP-19, also known as ARPP-19e, is a 121 amino acid protein that localizes to the cytoplasm and belongs to the endosulfine family. ENSA/ARPP-19 is an endogenous regulator of the _-cell K(ATP) channels and reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor thereby stimulating insulin secretion by pancreatic _ cells. It is suggested that ENSA/ARPP-19 expression is decreased in brains of both Alzheimer's disease (AD) and Down's syndrome patients. Widely expressed with high levels in skeletal muscle and brain and lower levels in pancreas, ENSA/ARPP-19 is phosphorylated by PKA and exists as eight alternatively spliced isoforms. ENSA/ARPP-19 is encoded by a gene located on human chromosome 1q21.3.
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