ATL1 抗体 (AA 201-300) (AbBy Fluor® 488)
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- 抗原 See all ATL1 抗体
- ATL1 (Atlastin GTPase 1 (ATL1))
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抗原表位
- AA 201-300
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ATL1 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SPG3A/Atlastin
- 亚型
- IgG
- Top Product
- Discover our top product ATL1 Primary Antibody
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anti-Atlastin GTPase 1 (ATL1) (N-Term) antibody
ATL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Atlastin GTPase 1 (ATL1) (AA 1-100) antibodyATL1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1F6B12 unconjugated
anti-Atlastin GTPase 1 (ATL1) (AA 1-280) antibodyATL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Atlastin GTPase 1 (ATL1) (AA 220-350) antibodyATL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Atlastin GTPase 1 (ATL1) antibodyATL1 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- ATL1 (Atlastin GTPase 1 (ATL1))
- 别名
- SPG3A/Atlastin (ATL1 产品)
- 别名
- ATL1 antibody, SPG3A antibody, fj46c01 antibody, wu:fj46c01 antibody, spg3a antibody, MGC146251 antibody, AD-FSP antibody, FSP1 antibody, GBP3 antibody, HSN1D antibody, SPG3 antibody, atlastin1 antibody, 4930435M24Rik antibody, Adfsp antibody, Fsp1 antibody, Spg3 antibody, Spg3a antibody, atlastin antibody, Atlastin-1 antibody, atlastin GTPase 1 antibody, ATL1 antibody, atl1 antibody, Atl1 antibody
- 背景
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Synonyms: AD FSP, atl1, ATLA1_HUMAN, Atlastin GTPase 1, Atlastin-1, Atlastin1, Brain specic GTP binding protein, Brain-specic GTP-binding protein, FSP1, GBP-3, GBP3, GTP-binding protein 3, Guanine nucleotide-binding protein 3, Guanylate binding protein 3, hGBP3, HSN1D, Spastic paraplegia 3 protein A, SPG 3A, SPG3, SPG3A.
Background: Atlastins are Golgi-localized, integral membrane proteins that function as GTPases. The Atlastin proteins, also designated SPG3A and guanylate-binding protein 3, comprise a Dynamin superfamily that plays a role in axonal maintenance. Hereditary spastic paraplegia (HSP) is an inherited neurodegenerative disorder that is characterized by retrograde axonal degeneration. HSP primarily affects long corticospinal neurons and causes spastic lower extremity weakness. Spastin, a microtubule (MT)-severing AAA ATPase, is a binding partner of Atlastin that is involved in membrane dynamics. This Spastin/Atlastin binding may be involved in the biochemical pathway that leads to HSP development. Mutations in the Atlastin gene (SPG3A) account for approximately 10 % of all autosomal dominant HSPs, while mutations in the Spastin gene (SPG4) account for almost 40 %.
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