RNF135 抗体 (AA 288-360) (AbBy Fluor® 488)
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- 抗原 See all RNF135 抗体
- RNF135 (Ring Finger Protein 135 (RNF135))
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抗原表位
- AA 288-360
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF135 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 预测反应
- Human,Mouse,Rat,Dog,Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human RNF135
- 亚型
- IgG
- Top Product
- Discover our top product RNF135 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- RNF135 (Ring Finger Protein 135 (RNF135))
- 别名
- RNF135 (RNF135 产品)
- 别名
- MMFD antibody, REUL antibody, Riplet antibody, 0610037N03Rik antibody, 2410006N06Rik antibody, LRRGT00184 antibody, ring finger protein 135 antibody, RNF135 antibody, Rnf135 antibody
- 背景
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Synonyms: L13, MGC13061, ring finger protein 135, RN135_HUMAN .
Background: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
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