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PQBP1 抗体 (AA 185-265) (AbBy Fluor® 350)

PQBP1 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 350
产品编号 ABIN1393107
发货至: 中国
  • 抗原 See all PQBP1 抗体
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    抗原表位
    • 14
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    AA 185-265
    适用
    • 34
    • 9
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 1
    宿主
    • 32
    • 3
    克隆类型
    • 32
    • 3
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PQBP1 antibody is conjugated to AbBy Fluor® 350
    应用范围
    • 29
    • 12
    • 12
    • 11
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PQBP1
    亚型
    IgG
    Top Product
    Discover our top product PQBP1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))
    别名
    PQBP1 (PQBP1 产品)
    别名
    PQBP1 antibody, MRX55 antibody, MRXS3 antibody, MRXS8 antibody, NPW38 antibody, RENS1 antibody, SHS antibody, PQBP-1 antibody, Sfc2 antibody, npw38 antibody, polyglutamine binding protein 1 antibody, PQBP1 antibody, Pqbp1 antibody
    背景

    Synonyms: 38 kDa nuclear protein containing a WW domain, Mental retardation, X linked 55, MRX55, MRXS3, MRXS8, Npw38, Nuclear protein containing WW domain 38 kD, Polyglutamine binding protein 1, Polyglutamine tract binding protein 1, Polyglutamine tract-binding protein 1, Polyglutamine-binding protein 1, PQBP 1, PQBP-1, PQBP1, PQBP1_HUMAN, RENS1, SHS, Sutherland Haan X linked mental retardation syndrome.

    Background: Polyglutamine(Q) tract binding protein-1 (PQBP-1) is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. Hepta- and di-amino acid repeat sequences rich in polar residues are essential for PQBP-1 to interact with polyglutamine tract-containing proteins (i.e. huntingtin, androgen receptor and Brain-2). PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. The human PQBP-1 gene maps to chromosome Xp11.23.

    途径
    Ribonucleoprotein Complex Subunit Organization
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