CTRP5 抗体 (AA 191-243) (AbBy Fluor® 350)
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- 抗原 See all CTRP5 (C1QTNF5) 抗体
- CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
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抗原表位
- AA 191-243
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CTRP5 antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CTRP5
- 亚型
- IgG
- Top Product
- Discover our top product C1QTNF5 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- CTRP5 (C1QTNF5) (C1q and Tumor Necrosis Factor Related Protein 5 (C1QTNF5))
- 别名
- CTRP5 (C1QTNF5 产品)
- 别名
- C1QTNF5 antibody, wu:fb02c10 antibody, wu:fb02f05 antibody, zgc:112378 antibody, CTRP5 antibody, Ctrp5 antibody, C1q and tumor necrosis factor related protein 5 antibody, C1q and TNF related 5 antibody, C1QTNF5 antibody, c1qtnf5 antibody, C1qtnf5 antibody
- 背景
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Synonyms: C1q and tumor necrosis factor related protein 5, C1QTNF5, Complement C1q tumor necrosis factor related protein 5 precursor, LORD, C1QT5_HUMAN.
Background: Members of the C1q superfamily have diverse functions that are related to cell adhesion and basement membrane components. CTRP5 (Complement C1q tumor necrosis factor-related protein 5) is a 243 amino acid secreted and membrane-associated protein that contains a collagen-like domain and a C1q domain. CTRP5 is a short-chain collagen that is expressed in retinal pigment epithelium as well as brain, lung, liver and placenta. By forming an extracellular hexagonal lattice, CTRP5 facilitates the adhesion of basal retinal pigment epithelium to Bruch?s membrane, the innermost layer of the choroid. A mutation within the C1q domain of CTRP5 results in abnormal high molecular weight aggregate formation, which alters its structure and interactions. This mutation may result in the presentation of late-onset retinal degeneration (LORD), an autosomal dominant disorder that is characterized by punctate yellow-white deposits in the retinal fundus and night blindness.
- 基因ID
- 114902
- UniProt
- Q9BXJ0
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