SH3PXD2A 抗体 (AA 261-360) (Biotin)
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- 抗原 See all SH3PXD2A 抗体
- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
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抗原表位
- AA 261-360
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适用
- 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SH3PXD2A antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 大鼠
- 预测反应
- Human,Mouse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FISH
- 亚型
- IgG
- Top Product
- Discover our top product SH3PXD2A Primary Antibody
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anti-SH3 and PX Domains 2A (SH3PXD2A) antibody
SH3PXD2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SH3 and PX Domains 2A (SH3PXD2A) (AA 1-1105) antibodySH3PXD2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-SH3 and PX Domains 2A (SH3PXD2A) (N-Term) antibodySH3PXD2A 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SH3PXD2A (SH3 and PX Domains 2A (SH3PXD2A))
- 别名
- FISH (SH3PXD2A 产品)
- 别名
- FISH antibody, SH3MD1 antibody, TKS5 antibody, 2310014D11Rik antibody, AA589508 antibody, AI256723 antibody, AI413738 antibody, C230050L11 antibody, EG329070 antibody, Fish antibody, Gm5098 antibody, Sh3md1 antibody, TSK5 antibody, Tks5 antibody, sh3pxd2a antibody, si:dkey-82d4.2 antibody, SH3 and PX domains 2A antibody, SH3 and PX domains 2Aa antibody, SH3PXD2A antibody, Sh3pxd2a antibody, sh3pxd2aa antibody
- 背景
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Synonyms: Adapter protein TKS5, Five SH3 domain-containing protein, SH3 and PX domain-containing protein 2A, SH3 multiple domains protein 1, Sh3md1, Sh3pxd2a, SPD2A_HUMAN, TKs5, Tyrosine kinase substrate with five SH3 domains.
Background: Fish, a potential Src substrate, is a broadly expressed adaptor protein containing five SH3 domains and a phox homology (PX) domain (1). The Src family of protein tyrosine kinases act in signal transduction pathways (2-4). Src kinases vary in expression but are strongly regulated in vivo, catalytic activity is repressed by interacting with the SH3 domain (5-7). In Src-transformed fibroblasts and in normal cells treated with certain growth factors fish is tyrosine-phosphorylated (1). Treatment of cells with cytochalasin D results in rapid tyrosine phosphorylation of fish, along with activation of Src (1). Fish is likely to be involved in tyrosine kinase signaling and may have a role in cytoskeletal changes (1).
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