APH1B 抗体 (AA 51-150) (Biotin)
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- 抗原 See all APH1B (Aph1b) 抗体
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
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抗原表位
- AA 51-150
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APH1B antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠
- 预测反应
- Human,Rat,Dog,Cow,Sheep,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Aph-1b
- 亚型
- IgG
- Top Product
- Discover our top product Aph1b Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
- 别名
- Aph-1b (Aph1b 产品)
- 别名
- APH-1B antibody, PRO1328 antibody, PSFL antibody, TAAV688 antibody, APH-1B' antibody, 2310057K14Rik antibody, Aph1c antibody, aph-1 homolog B, gamma-secretase subunit antibody, aph-1 homolog B, gamma secretase subunit antibody, aph1 homolog B, gamma secretase subunit antibody, APH1B antibody, Aph1b antibody
- 背景
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Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328
Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
- 基因ID
- 83464
- UniProt
- Q8WW43
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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