PKD1L3 抗体 (AA 121-220) (AbBy Fluor® 488)
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- 抗原 See all PKD1L3 抗体
- PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
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抗原表位
- AA 121-220
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PKD1L3 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PKD1L3
- 亚型
- IgG
- Top Product
- Discover our top product PKD1L3 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PKD1L3 (Polycystic Kidney Disease 1 Like 3 (PKD1L3))
- 别名
- PKD1L3 (PKD1L3 产品)
- 别名
- polycystic kidney disease 1 like 3 antibody, polycystin 1 like 3, transient receptor potential channel interacting antibody, Pkd1l3 antibody, PKD1L3 antibody
- 背景
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Synonyms: PC1 like 3 protein, Polycystic kidney disease 1 like 3, Polycystic kidney disease protein 1 like 3, Polycystin 1 like 3, Polycystin 1L3,PK1L3_HUMAN.
Background: Polycystin-1L3 is a 1,732 amino acid multi-pass membrane protein that contains one PLAT domain, one GPS domain and one C-type lectin domain. Expressed at high levels in placenta and present at lower levels in lung and heart, Polycystin-1L3 is thought to function as an ion-channel regulator that may interact with Polycystin-L and play a role in heteromeric taste channels. The gene encoding Polycystin-1L3 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
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