GUCA2A 抗体 (AA 22-115) (AbBy Fluor® 488)
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- 抗原 See all GUCA2A 抗体
- GUCA2A (Guanylate Cyclase Activator 2A (Guanylin) (GUCA2A))
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抗原表位
- AA 22-115
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GUCA2A antibody is conjugated to AbBy Fluor® 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Cow,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Guanylin
- 亚型
- IgG
- Top Product
- Discover our top product GUCA2A Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- GUCA2A (Guanylate Cyclase Activator 2A (Guanylin) (GUCA2A))
- 别名
- Guanylin (GUCA2A 产品)
- 别名
- GCAP-I antibody, GUCA2 antibody, STARA antibody, GUANYL antibody, Guanylin antibody, Guca2 antibody, GUCA2A antibody, guanylate cyclase activator 2A antibody, guanylate cyclase activator 2a (guanylin) antibody, guanylin antibody, GUCA2A antibody, Guca2a antibody, guc2a antibody
- 背景
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Synonyms: GapI, GCAP-I, Guanylate cyclase activating protein 1, Guanylate cyclase activator 2A guanylin 2 intestinal heat-stable, Guanylate cyclase activator 2A, Guanylate cyclase-activating protein 1, Guanylate cyclase-activating protein I, Guanylin, GUC2A_HUMAN, GUCA 2, GUCA2, GUCA2A, STARA.
Background: The family of guanylin regulatory peptides, including guanylin and uroguanylin, are strongly expressed in intestinal mucosa and regulate intestinal fluid secretion during digestion. Guanylins are also involved in acid neutralization and the regulation of membrane-bound guanylate cyclase signaling molecules. Guanylin and uroguanylin are secreted primarily in the stomach, intestine, and colon. Guanylin is also detected in plasma. Guanylin is an endogenous activator of intestinal guanylate cyclase. It stimulates intestinal guanylate cyclase through the same receptor binding region as the heat-stable enterotoxins. Gut enterochromaffin cells synthesize guanylin to be a prohormone of 115 amino acids which is then is processed to the molecular form of 94 amino acids. This 10 kDa form is found circulating in the blood.
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