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OTX1 抗体 (AA 1-100) (Biotin)

OTX1 适用: 人 ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal Biotin
产品编号 ABIN1392211
发货至: 中国
  • 抗原 See all OTX1 抗体
    OTX1 (Orthodenticle Homeobox 1 (OTX1))
    抗原表位
    • 14
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 65
    • 19
    • 18
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    宿主
    • 62
    • 3
    克隆类型
    • 62
    • 3
    多克隆
    标记
    • 25
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OTX1 antibody is conjugated to Biotin
    应用范围
    • 31
    • 25
    • 13
    • 13
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human OTX1
    亚型
    IgG
    Top Product
    Discover our top product OTX1 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    OTX1 (Orthodenticle Homeobox 1 (OTX1))
    别名
    OTX1 (OTX1 产品)
    别名
    A730044F23Rik antibody, jv antibody, OTX1X antibody, cb769 antibody, fj99f05 antibody, otx1 antibody, wu:fj99f05 antibody, zOtx1 antibody, otx1-A antibody, xotx1 antibody, otx1l antibody, otx3 antibody, orthodenticle homeobox 1 antibody, orthodenticle homeobox 1b antibody, orthodenticle homeobox 1 L homeolog antibody, orthodenticle homeobox 1a antibody, OTX1 antibody, Otx1 antibody, otx1b antibody, otx1.L antibody, otx1a antibody
    背景

    Synonyms: Homeobox protein OTX 1, Homeobox protein OTX1, MGC15736, Orthodenticle 1, Orthodenticle homeobox 1, Orthodenticle homolog 1, Orthodenticle1, Otx 1, otx1, OTX1_HUMAN.

    Background: Transcription factors, OTX1 and OTX2, are two murine homologs of the Drosophila orthodenticle (OTD), show a limited amino acid sequence divergence. OTX1 and OTX2 play an important role during early and later events required for proper brain development in that they are involved in the processes of induction, specification and regionalization of the brain. OTX1 is involved in corticogenesis, sensory organ development and pituitary functions, while OTX2 is necessary earlier in development, for the correct anterior neural plate specification and organization of the primitive streak. OTX2 is also required in the early specification of the neuroectoderm, which is destined to become the fore-midbrain, and both OTX1 and OTX2 co-operate in patterning the developing brain through a dosage-dependent mechanism. A molecular mechanism depending on a precise threshold of OTX proteins is necessary for the correct positioning of the isthmic region and for anterior brain patterning. The genes which encode OTX1 and OTX2 map to human chromosomes 2p15 and 14q21-q22, respectively.

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