NOMO1 抗体 (AA 701-800) (AbBy Fluor® 488)
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- 抗原 See all NOMO1 抗体
- NOMO1 (NODAL Modulator 1 (NOMO1))
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抗原表位
- AA 701-800
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOMO1 antibody is conjugated to AbBy Fluor® 488
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NOMO1
- 亚型
- IgG
- Top Product
- Discover our top product NOMO1 Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- NOMO1 (NODAL Modulator 1 (NOMO1))
- 别名
- NOMO1 (NOMO1 产品)
- 别名
- Nomo antibody, PM5 antibody, D7Ertd156e antibody, pM5 antibody, RGD1305240 antibody, NOMO2 antibody, DKFZP459L1733 antibody, Nomo1 antibody, NODAL modulator 1 antibody, nodal modulator 1 antibody, NOMO1 antibody, Nomo1 antibody, LOC515570 antibody, LOC714226 antibody, LOC100025365 antibody, LOC100174326 antibody, LOC100408200 antibody, LOC100464689 antibody, LOC100544619 antibody, LOC100626015 antibody, LOC454345 antibody, LOC489992 antibody, LOC100713781 antibody
- 背景
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Synonyms: Nodal modulator 1, NOMO 1, Nomo, NOMO1, NOMO1_HUMAN, PM5, pM5 protein, pM5 protein telomeric copy, NOMO1_HUMAN.
Background: Three highly similar proteins termed NOMO1, NOMO2 and NOMO3, are encoded by a gene mapping to a region of duplication on the p arm of human chromosome 16. All three NOMO proteins share similar functions and have been difficult to characterize individually. NOMO1 (Nodal modulator 1), also known as PM5, is a 1,222 amino acid highly conserved single-pass type I membrane protein expressed in colon tumor tissue and normal colonic mucosa. NOMO proteins are novel antagonists of Nodal signaling which interact with Nicalin to form a Nicalin-NOMO complex, and are rapidly degraded or stabilized by Nicalin. NOMO proteins were once considered candidates for the development of pseudoxanthoma elasticum (PXE), a heritable disorder of connective tissue, as the NOMO genes are located in close proximity to the gene responsible for PXE development (MRP6).
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