NAT8B 抗体 (AA 221-227) (AbBy Fluor® 350)
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- 抗原 See all NAT8B 抗体
- NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
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抗原表位
- AA 221-227
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAT8B antibody is conjugated to AbBy Fluor® 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- 预测反应
- Human,Mouse,Rat,Sheep,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NAT8B
- 亚型
- IgG
- Top Product
- Discover our top product NAT8B Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- NAT8B (N-Acetyltransferase 8B (GCN5-Related, Putative, Gene/pseudogene) (NAT8B))
- 别名
- NAT8B (NAT8B 产品)
- 别名
- EG434057 antibody, Cml1 antibody, Cml6 antibody, Nat8 antibody, RGD621605 antibody, CML2 antibody, Hcml2 antibody, NAT8BP antibody, N-acetyltransferase 8B antibody, N-acetyltransferase 8B, pseudogene antibody, N-acetyltransferase 8B (putative, gene/pseudogene) antibody, NAT8B antibody, Nat8b-ps antibody, Nat8b antibody
- 背景
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Synonyms: Camello like protein 2, Camello-like protein 2, CML2, Hcml2, N acetyltransferase 8B, NAT8B, NAT8B_HUMAN, NAT8BP, Probable N acetyltransferase 8B, Probable N-acetyltransferase 8B.
Background: Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-8B (N-acetyltransferase 8B), also known as CML2 (camello-like protein 2), is a 227 amino acid single-pass membrane protein that is implicated in gastrulation regulation. A member of the camello family, NAT-8B contains one N-acetyltransferase domain and is encoded by a gene that maps to human chromosome 2p13.2. The NAT-8B gene is susceptible to a nonsense mutation at Serine 16, which leads to a stop codon and subsequently, a non-functional protein that is truncated in length. Similarly, a nonsense mutation at Glutamine 168 is thought to lead to a non-functional protein, as it causes the N-acetyltransferase to become disrupted. Human chromosome 2 consists of 237 million bases, encodes over 1,400 genes and makes up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.
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